Breakthrough From Hanmi Life Sciences, IEONA GeneAKG Sets New Global Benchmark in Anti-Aging With Proprietary Patented Technology

ANYANG-SI, South Korea, October 22, 2026 (EZ Newswire) -- The global anti-aging industry is undergoing a profound transformation. IEONA GeneAKG®, developed by the Hanmi Life Sciences team under NextEye Co., Ltd. (Stock Code: 137940.KQ), is pioneering a shift from single-ingredient supplementation to systematic metabolic intervention through its world-first patented technology, three-dimensional synergistic formulation, and exclusive gender-specific solutions.

A World-First Milestone in Anti-Aging Innovation

As we age, mitochondrial function declines, reducing cellular energy metabolism efficiency. Alpha-ketoglutarate (AKG), a key intermediate in the tricarboxylic acid (TCA) cycle, plays a central role in energy metabolism. Endogenous AKG levels decrease with age, and supplementation may help restore cellular energy efficiency. Building on this principle, IEONA GeneAKG explores a new approach to slowing aging at its source.

Developed by the Hanmi Life Sciences team led by a Harvard-trained medical doctor, IEONA GeneAKG represents a world-first milestone in anti-aging innovation. In 2020, the team published animal research reporting that IEONA GeneAKG increased NAD+ and sirtuin protein levels, with effects on mitochondrial ATP production and DNA-related aging reversal reportedly surpassing those of NMN. The findings attracted widespread attention from the international medical community. Harvard professor David Sinclair, described as the discoverer of NMN, has also reportedly acknowledged IEONA GeneAKG's anti-aging potential on multiple occasions.

Proprietary Formulation and Gender-Specific Solutions Create a Competitive Advantage

Unlike conventional single-ingredient supplements, IEONA GeneAKG features a three-dimensional synergistic system designed to restore cellular function, promote cellular clearance, and boost energy metabolism. IEONA GeneAKG supports cellular function and reactivates energy metabolism; fisetin promotes cellular clearance and renewal; and pterostilbene enhances energy production by activating longevity-related pathways. Together, these ingredients form an integrated system designed to restore youthful metabolic balance.

IEONA GeneAKG offers gender-specific formulations. The men's formula combines saw palmetto extract and zinc to support prostate health, hormonal balance, and lean body mass maintenance. The women's formula incorporates phytoestrogen-like compounds to address skin laxity, bone loss, and cardiovascular risks associated with declining estrogen levels. This personalized, metabolism-based approach establishes a strong technological barrier to entry.

Three Synergistic Targets Supported by Scientific Data

Third-party efficacy evaluations of IEONA GeneAKG reported a 44.8% reduction in reactive oxygen species (ROS), supporting free radical clearance; up to a 53.2% increase in telomerase activity, associated with chromosome stability and cellular longevity; and up to a 77% increase in SPNS1 gene expression, potentially helping delay cellular aging. These three targets work synergistically across metabolism, cellular repair, and clearance.

IEONA GeneAKG has also undergone animal studies and human clinical trials. In a Phase I clinical trial conducted at NewMed Hospital in the United States, patients with chronic conditions reportedly experienced significant improvements across 13 common chronic diseases following oral administration, with 128 clinical indicators returning to normal ranges. These findings were presented as evidence of IEONA GeneAKG's safety and anti-aging efficacy in humans.

Beyond Cellular Health: Comprehensive Whole-Body Support

The potential benefits of IEONA GeneAKG extend to joint health, cognitive function, emotional well-being, and gut health. It supports cartilage cell vitality to help combat wear and inflammation, contributes to exercise-related improvements in spatial learning and memory formation, and helps maintain intestinal epithelial integrity and immune balance. From cellular health to whole-body wellness, it offers comprehensive anti-aging support.

IEONA GeneAKG is more than a product — it represents a measurable, reproducible rejuvenation solution. As the global anti-aging market evolves from luxury wellness toward science-based health solutions, IEONA GeneAKG aims to lead a new era of healthy aging through original research and proprietary technology.

Disclaimer

This press release is provided for informational purposes only and does not constitute medical, health, or clinical advice. Statements regarding IEONA GeneAKG® and its ingredients have not been evaluated by the U.S. Food and Drug Administration (FDA) or equivalent global health regulatory authorities. This product is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease, chronic condition, or medical ailment. Findings from preliminary animal research, preclinical evaluations, and pilot observational studies should not be interpreted as definitive clinical proof or guaranteed outcomes in humans. Individual results may vary based on physiological and metabolic factors. Readers should consult a qualified healthcare professional before making changes to their health regime or starting any new supplementation program. Mention of third-party academic institutions, researchers, or faculty members does not constitute an official endorsement or formal partnership unless explicitly declared by those entities.

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